By the time you reach the end of the game, there is only one person left for Spider-Man to defeat and that’s Doctor Octopus. Spider-Man has managed to apprehend five Sinister Six members, but now it’s time for their leader to fall as well.
Facing Doctor Octopus in the final battle is not that difficult, because all you really need to do is spam the circle button to avoid his attacks with his tentacles. Once you see an opening, you want to press triangle and then press square to punch his lights out.
It’s important that you keep pressing the circle button to dodge because you don’t want to get hit under any circumstances. At this stage of the game, Doctor Octopus can do a lot of damage on Spider-Man – especially if you are playing the game on one of the harder difficulty settings.
Doctor Octopus will have a second phase where the floor becomes lava (electrified) so you don’t want to stand on the ground. When the ground is electrified, you want to press the R2 and L2 buttons to find a pole that Spider-Man can perch on.
At this stage of the fight, Spider-Man has nowhere really to move because the pole is the only safe spot. Doctor Octopus will then throw a lot of junk and debris at Spider-Man, and this is where you can turn the tables on him.
If you see the junk approaching you, you want to now press R1 and L1 to throw the junk back at Doctor Octopus. It’s not very hard, although try to do it as soon as possible because you don’t want the debris to hit you!
Pretty much after that, Doctor Octopus will repeat his routine so just do the same method that is outlined above. Before long, a cinematic will play and all you need to do at the end of the fight are a series of quick time events (QTEs).
After doing the QTEs, then the final boss fight is over and you have completed the main story of Marvel’s Spider-Man PS4!