It appears that the 3rd game in the Zone of the Enders series is development. Now, before you rush out and pre-order it listen first. It was mentioned in a KojiPro report that Kojima had been working on it but he wants someone else to handle it since the team at Kojima Productions isn’t capable of doing so.
It wasn’t said who Kojima had in mind but if external developers are needed there’s a good chance it’ll be for current gen consoles.
If you can’t wait for ZOE3 you always have the HD collections that will soon be out on PS3, 360, and PS Vita.